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KMID : 0363620150360040056
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Journal of Korean Oriental Medicine
2015 Volume.36 No. 4 p.56 ~ p.68
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A Study about Quality Control of Herb Medicine Extract Granules About DanggwiSayeuggaosuyusaenggangtang(DSGOST)
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Sung Hyun-Kyung
Go Ho-Yeon
Sun Seung-Ho
Ko You-Me
Ko Seong-Gyu
Song Yun-Kyung
Kim Tae-Hoon
Sim Sung-Yong
Lee Hye-Lim
Jung Ki-Yong
Park Chong-Hyeong
Choi You-Kyung
Lee Min-Hye
Lim Eun-Mee
Jeon Chan-Yong
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Abstract
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Objectives: This study investigated quality among three herb medicine extract granules(DSGOST) which were made from different companies to check quality control of herb medicine extract granules.
Methods: we selected three DSGOST extract granules which were made from different companies. And we experimented extract granules by method from K.P(Korean Pharmacopoeia), K.H.P(Korean Herbal Pharmacopoeia) of KFDA.
Results: In qualitative analysis of DSGOST, we indentified Akebiae Caulis (木通), Asari Herba Cum Radix (細辛), Evodiae Fructus (吳茱萸) in three different DSGOST extract granules. In quantitative analysis of DSGOST, Medication A,B,C contained similar content of Paeoniflorin & Glycyrrhizic acid. However Medication B contains especially lowest value of Cinnamic acid & total Decursin.
Conclusions: Herb medicine extract granules have different contents of ingredients although those were made by same prescription. And these differences may influence medicinal effect to patients. So we need to make system of quality control with various research of quantitative & qualitative analysis about herb medicine extract granules.
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KEYWORD
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DSGOST(DanggwiSayeuggaosuyusaenggangtang), herb medicine extract granules, quality control
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